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ea0034p218 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2014

Young women with polycystic ovary syndrome have increased concentrations of circulating annexin V-positive microparticles derived predominantly from platelets

Willis Gareth , Connolly Katherine , Ladell Kristin , Miners Kelly , Price David , Guschina Irina , Clayton Aled , James Philip , Rees Aled

Background: Women with polycystic ovary syndrome (PCOS) may have increased cardiovascular (CV) risk but the mechanisms are unclear. Microparticles (MP), small circulating vesicles released from platelets, monocytes and endothelial cells, are elevated in patients with CV disease, and may increase CV risk through altered cell content and/or increased surface exposure of procoagulant phosphatidylserine (PS).Aims: To compare MP characteristics between women ...

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Endocrine Abstracts

Young women with polycystic ovary syndrome have increased concentrations of circulating annexin V-positive microparticles derived predominantly from platelets

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